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STIMA 1
CAS No. 91634-12-7
STIMA 1( STIMA1 )
Catalog No. M16581 CAS No. 91634-12-7
STIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 42 | Get Quote |
|
| 10MG | 59 | Get Quote |
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| 25MG | 87 | Get Quote |
|
| 50MG | 164 | Get Quote |
|
| 100MG | 248 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSTIMA 1
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NoteResearch use only, not for human use.
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Brief DescriptionSTIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro.
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DescriptionSTIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro, induces expression of p53 target proteins and triggers apoptosis in mutant p53-expressing human tumor cells.
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In Vitro——
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In Vivo——
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SynonymsSTIMA1
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PathwayApoptosis
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TargetMDM2-p53
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RecptorMDM2-p53
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Research Area——
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Indication——
Chemical Information
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CAS Number91634-12-7
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Formula Weight172.187
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Molecular FormulaC10H8N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (1451.97 mM)
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SMILESC=CC1=NC2=CC=CC=C2C(=O)N1
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Chemical Name2-ethenyl-1H-quinazolin-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zache N, et al. Mol Oncol. 2008 Jun;2(1):70-80.
2. Bykov VJ, et al. FEBS Lett. 2014 Aug 19;588(16):2622-7.
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STIMA 1
STIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro.
